Impact of Dexamethasone on COVID-19 Patients

Authors: Widad M. Al-Bishri(1), Ghadeer H. Alhazmi (2), Barah M. Sulaiman (3), Duaa M. Mandeeli (4), Bashayer F. AlSulaymani (5), Adyan k. Qurban (6)
Department of Biochemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia (1)
Bachelor of medical laboratory, Laboratory specialist in Maternity and Children Hospital, Makkah, Saudi Arabia (2,3.4), Bachelor of genomics and biotechnology, Medical Laboratory Department, Collage of Applied Medical Science, University of Jeddah, Jeddah, Saudi Arabia (5),
Bachelor of pharmacy, Pharmacist, Bayer Consumer Health Care, Makkah, Saudi Arabia (6)



The coronavirus infection 19 (COVID-19) is an extremely contagious as well as infectious agent’s viral illness generated by the extreme acute respiratory disorder coronavirus which called (SARS-CoV-2) virus, which first appeared in Wuhan as well as China, and has since spread throughout the world. The 2019 Coronavirus Infection (COVID-19) is linked to diffuse lung injury. Corticosteroids can help to prevent respiratory damage as well as death by modulating inflammation injury occurs in the lung. The aim of this literature review is to obtain a knowledge of current studies as well as debates related to this specific research subject, as well as the objectives of this research were to look at the anti-inflammatory effects of corticosteroids (particularly dexamethasone) in individuals with COVID-19-induced moderate-to-severe Acute respiratory distress syndrome (ARDS). It also described the pathway of glucocorticoid metabolic effects as well as illustrated some adverse effects of dexamethasone on various organs in COVID-19 patients. According to the findings, small quantities of corticosteroids (dexamethasone) can minimize mortality with serious COVID-19 disorder.


Coronavirus, Dexamethasone, Corticosteroids, Respiratory viruses, Treated

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ISSN: 2706-6495

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